Mercurial diuretics; the replacement of parenteral administration by a new oral preparation in ambulatory patients with chronic congestive heart failure.
نویسندگان
چکیده
Improvement in the usage of an effective therapeutic agent is highly desirable especially when the method of administration is simplified, the total dosage reduced, the toxicity of the drug diminished and the cost of medical care lessened. The replacement of parenteral injections of the mercurial diuretics by an oral preparation in ambulatory patients in chronic congestive heart failure represents a step forward in the management of this type of patient.
منابع مشابه
The Prolonged Use of an Oral Mercurial Diuretic in Ambulatory Patients with Congestive Heart Failure
Tablets of an oral mercurial diuretic were utilized in the management of patients with severe congestive failure over a prolonged period of time. The need for parenteral mercurial diuretics wvas eliminated or greatly decreased by this therapy. The individual dosage was established by clinical trial. _Minor toxic effects were encountered in several patients but in all instances it was p)ossible ...
متن کاملClinical evaluation of a new oral nonmercurial diuretic.
The oral administration of the organomercurial drugs in patients requiring prolonged management of congestive failure has been rather unsatisfactory because of occasional toxic signs and symptoms. With the development of the pyrimidinedione derivatives as diuretic agents and encouraging pharmacologic studies in animals, clinical trial is warranted. A group of 24 patients who had received inject...
متن کاملA reversible nephrotic syndrome associated with congestive heart failure.
Attemition is drawn to the occurrence of the nephrotic syndrome duriiig chronic heam't failure and to its reversibility over a period of months on a regimen of digitalis, lowsalt diet, and weekly, parenterally administered, mercurial diuretics. It is therefore concluded that the nephrotic syndrome was not caused by mercurial diuretics and is not a eontraindication to their use. Reference is ama...
متن کاملHuman Blood Groups and Inheritance
Mercury Crystals from the Vapor" or "Oxymercuration of Alkenes." There is a good summary of "Relationship between Clinical Structure and Biological Activity in Mercurial Compounds," by Harris L. Friedman, a brief section, with references, on "Toxicology of Inorganic Mercury" by Leonard J. Goldwater, and an excellent short discussion by Alvin Farah of histochemical techniques for localizing the ...
متن کاملTreatment of the low-salt syndrome in congestive heart failure by the controlled use of mercurial diuretics.
The production of the low-salt syndrome in cardiac patients with refractory congestive heart failure is generally attributed either to fluid retention with electrolyte dilution or to excessive salt loss, induced by the frequent administration of mercurial diuretics. The former is often the important etiologic factor. In a study of a group of 25 refractory cardiac patients with normal plasma ele...
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ورودعنوان ژورنال:
- Circulation
دوره 7 3 شماره
صفحات -
تاریخ انتشار 1953